Whether you're playing as Leon or Claire, the solutions remain the same and can be accessed without grabbing the memo that hints at their solution. The only exception to this are the items you grab by developing film rolls--though, there is a minor exception even to that. Regardless, below you can find details on all the optional items locked behind safes, lockers, or hidden in the environment.
They are usually intended for use in public places, and intended for the short- or long-term private use of individuals for storing clothing or other personal items. Users may rent a locker for a single use or for a period of time for repeated use. Some lockers are offered as a free service to people partaking of certain activities that require the safekeeping of personal items.