There are a bunch of items and resources in Resident Evil 2 that are completely optional, such as hip pouches that expand your inventory space or ammo for some of your most powerful guns. These are typically hidden inside safes or lockers with letter dial locks. You can find the combinations for these either in memos or even scribbled somewhere on a wall.
Examine the scepter to obtain the Red Jewel. This goes into the Bejeweled Box, which you can get in the Interrogation Room. Accessing this area requires the Club Key, so if you don't have that yet, keep progressing the story until you get it. Once you've got the Bejeweled Box, combine it with the Red Jewel to get the S.T.A.R.S. badge. You can use this item in two locations: the Underground Stairs in the Middle section of the Underground Facility, and the S.T.A.R.S. Office.
Clean/dirty lockers normally have two or three parts within the locker. One part is meant for dirty or clothes that are worn, and the other side for clean clothes. These lockers are meant for hospitals or other medical workplaces where it is useful to keep work and personal clothes apart to reduce the risk of infection. These lockers are also useful for factories where work clothes can become dirty and it can be very useful to keep them apart from personal clothes.
Perforated lockers are similar to the standard types of locker, but the door and walls are made largely or entirely of perforated steel, with hundreds of holes creating a strong mesh arranged in a diagonal pattern. This is used where good ventilation is required, or where, for security reasons, it is necessary that the contents can be examined visually while the doors are locked.
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